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Homer 1b/c (AA 152-354) antibody

The Rabbit Polyclonal anti- antibody has been validated for WB and ICC. It is suitable to detect in samples from Human, Mouse and Rat. There are 3+ publications available.
Catalog No. ABIN1742339

Quick Overview for Homer 1b/c (AA 152-354) antibody (ABIN1742339)

Target

Homer 1b/c

Reactivity

Human, Mouse, Rat

Host

  • 1
Rabbit

Clonality

  • 1
Polyclonal

Conjugate

  • 1
Un-conjugated

Application

  • 1
  • 1
  • 1
Western Blotting (WB), Immunocytochemistry (ICC)
  • Binding Specificity

    AA 152-354

    Specificity

    Specific for homer 1b and 1c

    Cross-Reactivity (Details)

    no cross-reactivity to homer 1a.

    Purification

    Affinity purified with the immunogen.

    Immunogen

    Purified recombinant protein (aa 152-354 of human homer1b)
  • Application Notes

    WB: 1:1000, ICC: 1:500, IHC: 1:200 up to 1:500,

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    For reconstitution add 50µl H2O to get a 1mg/ml solution in PBS.

    Buffer

    PBS. Albumin and azide were added for stabilization.

    Preservative

    Sodium azide

    Handling Advice

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    Storage

    -20 °C

    Storage Comment

    Reconstitute and aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized.
  • Yoon, Piguel, Khalatyan, Dionisio, Savas, Penzes: "Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome." in: Molecular psychiatry, (2021) (PubMed).

    Kim, Kong, Yamamoto, Kuramoto, Huang, Wang, Hong, Xiao, Levine, Qiu, Zhao, Miller, Dong, Meltzer, Xu, He: "An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system." in: Science advances, Vol. 7, Issue 8, (2021) (PubMed).

    Tao-Cheng, Thein, Yang, Reese, Gallant: "Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation." in: Neuroscience, Vol. 266, pp. 80-90, (2014) (PubMed).

  • Target

    Homer 1b/c

    Background

    Synonyms: VesL 1, Syn47
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